MolNFT v1 · #24889 · protein
Crystal structure analysis of bovine carbonic anhydrase II
1V9E: “Crystal structure analysis of bovine carbonic anhydrase II”. X-ray diffraction, 1 ligand (ZN), 4 pockets (best druggability 0.46). MolNFT v1 #24889 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1V9E
- Type
- protein
- Length
- 518 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carbonic anhydrase II
- EC
- 4.2.1.1
- UniProt
- P00921
- Ligands
- ZN
- Pockets
- 4 · best druggability 0.46
Structure
x-ray diffraction · 1 distinct chain · 15% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Carbonic anhydrase II (EC 4.2.1.1) | protein | 259 | 15% helix, 30% strand | P00921 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 129 | 0.46 | 0.77 | 23 | empty |
| 2 | 79 | 0.44 | 0.80 | 21 | empty |
| 3 | 76 | 0.35 | 0.75 | 16 | empty |
| 4 | 67 | 0.33 | 0.76 | 17 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00921
- Elsewhere: RCSB PDB 1V9E · PDBe 1V9E · UniProt P00921
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