MolNFT v1 · #24887 · protein
Crystal analysis of precorrin-8X methyl mutase from thermus thermophilus
1V9C: “Crystal analysis of precorrin-8X methyl mutase from thermus thermophilus”. X-ray diffraction, 2 ligands (SO4, CL), 2 pockets (best druggability 0.77). MolNFT v1 #24887 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1V9C
- Type
- protein
- Length
- 404 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Precorrin-8X methyl mutase
- EC
- 5.4.1.2
- UniProt
- P83848
- Ligands
- SO4, CL
- Pockets
- 2 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Precorrin-8X methyl mutase (EC 5.4.1.2) | protein | 198 | 52% helix, 11% strand | P83848 |
| B | Precorrin-8X methyl mutase (EC 5.4.1.2) | protein | 206 | 53% helix, 10% strand | P83848 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 768 | 0.77 | 0.81 | 60 | SO4 |
| 2 | 660 | 0.75 | 0.81 | 40 | SO4 |
Interfaces
1 interface between chains.
- A–B · 1107 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 1V9C · Crystal Analysis of Precorrin-8x Methyl Mutase from Thermus Thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P83848
- Elsewhere: RCSB PDB 1V9C · PDBe 1V9C · UniProt P83848
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