MolNFT v1 · #24789 · protein

Solution structure of the third PDZ domain of mouse harmonin

1V6B · Harmonin isoform A1: “Solution structure of the third PDZ domain of mouse harmonin”. Solution nmr, 1 pocket (best druggability 0.27). MolNFT v1 #24789 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1V6B
Type: protein
Length: 118 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Harmonin isoform A1
UniProt: Q9ES64
Pockets: 1 · best druggability 0.27

Structure

solution nmr · 1 distinct chain · 19% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Harmonin isoform A1	protein	118	19% helix, 26% strand	Q9ES64

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.27	0.73	16	empty

Compared structures

1V6B · Solution structure of the third PDZ domain of mouse harmonin · the same entry in another collection · chain A against A, TM-score 1.00
Q9ES64 · AlphaFold monomer V2.0 prediction for harmonin (Q9ES64) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ES64
Elsewhere: RCSB PDB 1V6B · PDBe 1V6B · UniProt Q9ES64

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