MolNFT v1 · #24781 · protein
Solution structure of the pleckstrin homology domain of alpha-pix
1V61 · RAC/CDC42 guanine nucleotide exchange factor (gef) 6: “Solution structure of the pleckstrin homology domain of alpha-pix”. Solution nmr, 1 pocket (best druggability 0.39). MolNFT v1 #24781 on GenesisL1: 3D structure, binding sites…
- PDB
- 1V61
- Type
- protein
- Length
- 132 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RAC/CDC42 guanine nucleotide exchange factor (gef) 6
- Pockets
- 1 · best druggability 0.39
Structure
solution nmr · 1 distinct chain · 11% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAC/CDC42 guanine nucleotide exchange factor (gef) 6 | protein | 132 | 11% helix, 25% strand | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 103 | 0.39 | 0.75 | 17 | empty |
Compared structures
- 1V61 · Solution Structure of the Pleckstrin Homology Domain of alpha-Pix · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1V61 · PDBe 1V61
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