MolNFT v1 · #24777 · protein
Crystal structure of phosphoribosyl anthranilate isomerase from thermus thermophilus
1V5X · Phosphoribosylanthranilate isomerase: “Crystal structure of phosphoribosyl anthranilate isomerase from thermus thermophilus”. X-ray diffraction, 4 pockets (best druggability 0.71). MolNFT v1 #24777 on GenesisL1: 3D structure…
- PDB
- 1V5X
- Type
- protein
- Length
- 400 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosylanthranilate isomerase
- EC
- 5.3.1.24
- UniProt
- P83825
- Pockets
- 4 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 37% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Phosphoribosylanthranilate isomerase (EC 5.3.1.24) | protein | 200 | 37% helix, 22% strand | P83825 |
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 182 | 0.71 | 0.88 | 32 | empty |
| 2 | 183 | 0.68 | 0.87 | 34 | empty |
| 3 | 527 | 0.67 | 0.78 | 40 | empty |
| 4 | 366 | 0.66 | 0.80 | 50 | empty |
Interfaces
1 interface between chains.
- A–B · 1292 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 1V5X · Crystal structure of Phosphoribosyl anthranilate isomerase from Thermus Thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P83825
- Elsewhere: RCSB PDB 1V5X · PDBe 1V5X · UniProt P83825
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