MolNFT v1 · #24648 · protein
Crystal structure of prib- a primosomal DNA replication protein of escherichia COLI
1V1Q · Primosomal replication protein N: “Crystal structure of prib- a primosomal DNA replication protein of escherichia COLI”. X-ray diffraction, 1 ligand (CYS), 1 pocket (best druggability 0.46). MolNFT v1 #24648 on GenesisL1: 3D…
- PDB
- 1V1Q
- Type
- protein
- Length
- 221 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Primosomal replication protein N
- UniProt
- P07013
- Ligands
- CYS
- Pockets
- 1 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 7% helix, 60% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Primosomal replication protein N | protein | 110 | 8% helix, 62% strand | P07013 |
| B | Primosomal replication protein N | protein | 111 | 5% helix, 58% strand | P07013 |
Ligands and binding sites
- CYS · Cysteine · ligand · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 124 | 0.46 | 0.78 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 1998 Ų buried · 24 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 covalent, 2 disulfide (covalent ligand, disulfide).
Compared structures
- 1V1Q · Crystal structure of PriB- a primosomal DNA replication protein of Escherichia coli · the same entry in another collection · chain A against A, TM-score 1.00
- P07013 · AlphaFold monomer V2.0 prediction for primosomal replication protein N (P07013) · a predicted model of the same protein · chain B against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07013
- Elsewhere: RCSB PDB 1V1Q · PDBe 1V1Q · UniProt P07013
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