MolNFT v1 · #24589 · protein

Integrin binding CBEGF22-TB4-CBEGF33 fragment of human fibrillin-1, apo form CBEGF23 domain only.

1UZQ: “Integrin binding CBEGF22-TB4-CBEGF33 fragment of human fibrillin-1, apo form CBEGF23 domain only.”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #24589 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1UZQ
Type: protein
Length: 152 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibrillin-1
UniProt: P35555
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fibrillin-1	protein	152	14% helix, 36% strand	P35555

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.30	0.75	14	empty

Modifications

Observed in the structure: 10 disulfide (disulfide).

Compared structures

1UZQ · Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, apo form cbEGF23… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35555
Elsewhere: RCSB PDB 1UZQ · PDBe 1UZQ · UniProt P35555

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