MolNFT v1 · #24347 · protein

Putative styrene monooxygenase small component with bound NADP+

1USF: “Putative styrene monooxygenase small component with bound NADP+”. X-ray diffraction, 2 ligands (NAP, FMN), 3 pockets (best druggability 0.75). MolNFT v1 #24347 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1USF
Type: protein
Length: 356 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative styrene monooxygenase small component
Ligands: NAP, FMN
Pockets: 3 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Putative styrene monooxygenase small component	protein	178	12% helix, 46% strand	—

Ligands and binding sites

NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · 4 copies · chains A, B
FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
GOL · Glycerol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.75	0.98	21	empty
2	298	0.61	0.79	38	FMN, NAP, GOL
3	286	0.59	0.78	39	FMN, NAP, GOL

Interfaces

1 interface between chains.

A–B · 3690 Å² buried · 46 hydrogen bonds · protein-protein

Compared structures

1USF · Putative styrene monooxygenase small component with bound NADP+ · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1USF · PDBe 1USF

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