MolNFT v1 · #24324 · protein
Crystal structure of neuronal Q-snares in complex with R-snare motif of tomosyn
1URQ · M-tomosyn isoform: “Crystal structure of neuronal Q-snares in complex with R-snare motif of tomosyn”. X-ray diffraction. MolNFT v1 #24324 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1URQ
- Type
- protein
- Length
- 252 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- M-tomosyn isoform; Syntaxin 1A; Synaptosomal-associated protein 25
- UniProt
- Q9Z152, P32851, P13795
Structure
x-ray diffraction · 4 distinct chains · 94% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | M-tomosyn isoform | protein | 58 | 95% helix, 0% strand | Q9Z152 |
| B | Syntaxin 1A | protein | 64 | 94% helix, 0% strand | P32851 |
| C | Synaptosomal-associated protein 25 | protein | 68 | 94% helix, 0% strand | P13795 |
| D | Synaptosomal-associated protein 25 | protein | 62 | 94% helix, 0% strand | P13795 |
Interfaces
6 interfaces between chains.
- A–B · 1542 Ų buried · 4 hydrogen bonds · protein-protein
- B–C · 1522 Ų buried · 14 hydrogen bonds · protein-protein
- C–D · 1507 Ų buried · 16 hydrogen bonds · protein-protein
- A–D · 1206 Ų buried · 13 hydrogen bonds · protein-protein
- A–C · 348 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 1URQ · Crystal structure of neuronal Q-SNAREs in complex with R-SNARE motif of Tomosyn · the same entry in another collection · chain A against A, TM-score 1.00
- P32851 · AlphaFold monomer V2.0 prediction for syntaxin-1A (P32851) · a predicted model of the same protein · chain B against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Z152
- Every structure of UniProt P32851
- Every structure of UniProt P13795
- Elsewhere: RCSB PDB 1URQ · PDBe 1URQ · UniProt Q9Z152 · UniProt P32851 · UniProt P13795
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