MolNFT v1 · #24078 · protein

Solution structure of the fourth PDZ domain of human scribble (KIAA0147 protein)

1UJU: “Solution structure of the fourth PDZ domain of human scribble (KIAA0147 protein)”. Solution nmr, 1 pocket (best druggability 0.35). MolNFT v1 #24078 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1UJU
Type: protein
Length: 111 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Scribble
UniProt: Q14160
Pockets: 1 · best druggability 0.35

Structure

solution nmr · 1 distinct chain · 12% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Scribble	protein	111	12% helix, 19% strand	Q14160

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.35	0.79	17	empty

Compared structures

1UJU · Solution structure of the fourth PDZ domain of human scribble (KIAA0147 protein) · the same entry in another collection · chain A against A, TM-score 1.00
Q14160 · AlphaFold monomer V2.0 prediction for protein scribble homolog (Q14160) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14160
Elsewhere: RCSB PDB 1UJU · PDBe 1UJU · UniProt Q14160

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