MolNFT v1 · #23911 · protein

Solution structure of ubiquitin-like domain of HHR23B complexed with ubiquitin-interacting motif of proteasome subunit S5A

1UEL · UV excision repair protein RAD23 homolog B: “Solution structure of ubiquitin-like domain of HHR23B complexed with ubiquitin-interacting motif of…”. Solution nmr, 1 pocket (best druggability 0.48). MolNFT v1 #23911 on GenesisL1: 3D…

PDB: 1UEL
Type: protein
Length: 143 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: UV excision repair protein RAD23 homolog B; 26S proteasome non-ATPase regulatory subunit 4
UniProt: P54727, P55036
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 2 distinct chains · 24% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	UV excision repair protein RAD23 homolog B	protein	95	21% helix, 27% strand	P54727
B	26S proteasome non-ATPase regulatory subunit 4	protein	48	31% helix, 0% strand	P55036

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.48	0.81	20	empty

Interfaces

1 interface between chains.

A–B · 756 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

1UEL · Solution structure of ubiquitin-like domain of hHR23B complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
P54727 · AlphaFold monomer V2.0 prediction for UV excision repair protein RAD23 homolog B (P54727) · a predicted model of the same protein · chain A against A, TM-score 0.76
P55036 · AlphaFold monomer V2.0 prediction for 26S proteasome non-ATPase regulatory subunit 4… · a predicted model of the same protein · chain B against A, TM-score 0.42

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P54727
Every structure of UniProt P55036
Elsewhere: RCSB PDB 1UEL · PDBe 1UEL · UniProt P54727 · UniProt P55036

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