MolNFT v1 · #2386 · protein

Human erythropoietin, NMR minimized average structure

1BUY · Protein (erythropoietin): “Human erythropoietin, NMR minimized average structure”. Solution nmr, 2 pockets (best druggability 0.50). MolNFT v1 #2386 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1BUY
Type: protein
Length: 166 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (erythropoietin)
UniProt: P01588
Pockets: 2 · best druggability 0.50

Structure

solution nmr · 1 distinct chain · 57% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (erythropoietin)	protein	166	57% helix, 1% strand	P01588

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	116	0.50	0.80	17	empty
2	67	0.32	0.75	23	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1BUY · Human erythropoietin, NMR minimized average structure · the same entry in another collection · chain A against A, TM-score 1.00
P01588 · AlphaFold monomer V2.0 prediction for erythropoietin (P01588) · a predicted model of the same protein · chain A against A, TM-score 0.80

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01588
Elsewhere: RCSB PDB 1BUY · PDBe 1BUY · UniProt P01588

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