MolNFT v1 · #23855 · protein

Complex of transaldolase with the reduced schiff-base intermediate

1UCW: “Complex of transaldolase with the reduced schiff-base intermediate”. X-ray diffraction, 2 pockets (best druggability 0.33). MolNFT v1 #23855 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1UCW
Type: protein
Length: 632 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transaldolase
EC: 2.2.1.2
UniProt: P0A870
Pockets: 2 · best druggability 0.33

Structure

x-ray diffraction · 1 distinct chain · 57% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Transaldolase (EC 2.2.1.2)	protein	316	57% helix, 13% strand	P0A870

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.33	0.75	16	empty
2	70	0.33	0.75	16	empty

Interfaces

1 interface between chains.

A–B · 137 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 2 modified (nonstandard).

Compared structures

1UCW · Complex of transaldolase with the reduced schiff-base intermediate · the same entry in another collection · chain A against A, TM-score 1.00
P0A870 · AlphaFold monomer V2.0 prediction for transaldolase B (P0A870) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A870
Elsewhere: RCSB PDB 1UCW · PDBe 1UCW · UniProt P0A870

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