MolNFT v1 · #23509 · protein

Crystal structure of a-dystroglycan

1U2C: “Crystal structure of a-dystroglycan”. X-ray diffraction, 1 pocket (best druggability 0.54). MolNFT v1 #23509 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1U2C
Type: protein
Length: 228 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dystroglycan
UniProt: Q62165
Pockets: 1 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 19% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dystroglycan	protein	228	19% helix, 36% strand	Q62165

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	314	0.54	0.75	34	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1U2C · Crystal Structure of a-dystroglycan · the same entry in another collection · chain A against A, TM-score 1.00
Q62165 · AlphaFold monomer V2.0 prediction for dystroglycan (Q62165) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q62165
Elsewhere: RCSB PDB 1U2C · PDBe 1U2C · UniProt Q62165

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