MolNFT v1 · #23432 · protein
Crystal structure of full length argonaute from pyrococcus furiosus
1U04 · Hypothetical protein PF0537: “Crystal structure of full length argonaute from pyrococcus furiosus”. X-ray diffraction, 6 pockets (best druggability 0.75). MolNFT v1 #23432 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1U04
- Type
- protein
- Length
- 713 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein PF0537
- UniProt
- Q8U3D2
- Pockets
- 6 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical protein PF0537 | protein | 713 | 33% helix, 28% strand | Q8U3D2 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 575 | 0.75 | 0.82 | 72 | empty |
| 2 | 631 | 0.69 | 0.77 | 62 | empty |
| 3 | 396 | 0.58 | 0.74 | 38 | empty |
| 4 | 212 | 0.49 | 0.75 | 29 | empty |
| 5 | 64 | 0.38 | 0.78 | 14 | empty |
Modifications
Observed in the structure: 18 modified (engineered).
Compared structures
- 1U04 · Crystal structure of full length Argonaute from Pyrococcus furiosus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8U3D2
- Elsewhere: RCSB PDB 1U04 · PDBe 1U04 · UniProt Q8U3D2
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