MolNFT v1 · #2339 · protein

Human serum transferrin, recombinant N-terminal lobe, apo form, crystal form 2

1BTJ · Protein (serum transferrin): “Human serum transferrin, recombinant N-terminal lobe, apo form, crystal form 2”. X-ray diffraction, 4 pockets (best druggability 0.36). MolNFT v1 #2339 on GenesisL1: 3D structure, binding sites and…

PDB: 1BTJ
Type: protein
Length: 666 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (serum transferrin)
UniProt: P02787
Pockets: 4 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Protein (serum transferrin)	protein	333	35% helix, 21% strand	P02787

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	109	0.36	0.74	24	empty
2	106	0.36	0.74	23	empty
3	62	0.32	0.76	15	empty
4	57	0.31	0.76	15	empty

Modifications

Observed in the structure: 16 disulfide (disulfide).

Compared structures

1BTJ · Human serum transferrin, recombinant N-terminal lobe, apo form, crystal form 2 · the same entry in another collection · chain A against A, TM-score 1.00
P02787 · AlphaFold monomer V2.0 prediction for serotransferrin (P02787) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02787
Elsewhere: RCSB PDB 1BTJ · PDBe 1BTJ · UniProt P02787

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