MolNFT v1 · #23120 · protein

Crystal structure of a. fulgidus RIO2 serine protein kinase

1TQI · Conserved hypothetical protein: “Crystal structure of a. fulgidus RIO2 serine protein kinase”. X-ray diffraction, 3 pockets (best druggability 0.59). MolNFT v1 #23120 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1TQI
Type: protein
Length: 269 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Conserved hypothetical protein
UniProt: O30245
Pockets: 3 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Conserved hypothetical protein	protein	269	45% helix, 21% strand	O30245

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	239	0.59	0.79	29	empty
2	63	0.37	0.78	14	empty
3	52	0.30	0.76	11	empty

Compared structures

1TQI · Crystal Structure of A. Fulgidus Rio2 Serine Protein Kinase · the same entry in another collection · chain A against A, TM-score 1.00
O30245 · AlphaFold monomer V2.0 prediction for rio-type SERINE/THREONINE- protein kinase RIO2… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O30245
Elsewhere: RCSB PDB 1TQI · PDBe 1TQI · UniProt O30245

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