MolNFT v1 · #23060 · protein

Rat submaxillary gland serine protease, tonin. structure solution and refinement at 1.8 ångströms resolution

1TON: “Rat submaxillary gland serine protease, tonin. structure solution and refinement at 1.8 ångströms resolution”. X-ray diffraction, 1 ligand (ZN), 2 pockets (best druggability 0.44). MolNFT v1 #23060 on GenesisL1: 3D structure…

PDB: 1TON
Type: protein
Length: 227 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tonin
UniProt: P00759
Ligands: ZN
Pockets: 2 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tonin	protein	227	12% helix, 33% strand	P00759

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	81	0.44	0.81	18	empty
2	78	0.33	0.74	19	empty

Modifications

Observed in the structure: 5 disulfide (disulfide).

Compared structures

1TON · Rat submaxillary gland serine protease, tonin. structure solution and refinement at 1.8… · the same entry in another collection · chain A against A, TM-score 1.00
P00759 · AlphaFold monomer V2.0 prediction for tonin (P00759) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00759
Elsewhere: RCSB PDB 1TON · PDBe 1TON · UniProt P00759

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.