MolNFT v1 · #23036 · protein

NMR solution structure of calcium saturated skeletal muscle troponin C

1TNW: “NMR solution structure of calcium saturated skeletal muscle troponin C”. Solution nmr, 3 pockets (best druggability 0.39). MolNFT v1 #23036 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1TNW
Type: protein
Length: 162 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Troponin C
UniProt: P02588
Pockets: 3 · best druggability 0.39

Structure

solution nmr · 1 distinct chain · 57% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Troponin C	protein	162	57% helix, 2% strand	P02588

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.39	0.80	9	empty
2	80	0.35	0.76	19	empty
3	58	0.33	0.75	13	empty

Compared structures

1TNW · NMR solution structure of calcium saturated skeletal muscle troponin C · the same entry in another collection · chain A against A, TM-score 1.00
P02588 · AlphaFold monomer V2.0 prediction for troponin C, skeletal muscle (P02588) · a predicted model of the same protein · chain A against A, TM-score 0.49

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02588
Elsewhere: RCSB PDB 1TNW · PDBe 1TNW · UniProt P02588

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