MolNFT v1 · #23029 · protein
Structures of the apo and calcium troponin-C regulatory domains: the muscle contraction switch
1TNP · Troponin-C (apo): “Structures of the apo and calcium troponin-C regulatory domains: the muscle contraction switch”. Solution nmr, 2 pockets (best druggability 0.41). MolNFT v1 #23029 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1TNP
- Type
- protein
- Length
- 90 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Troponin-C (apo)
- UniProt
- P02588
- Pockets
- 2 · best druggability 0.41
Structure
solution nmr · 1 distinct chain · 61% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Troponin-C (apo) | protein | 90 | 61% helix, 4% strand | P02588 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 100 | 0.41 | 0.77 | 20 | empty |
| 2 | 62 | 0.34 | 0.77 | 13 | empty |
Compared structures
- 1TNP · Structures of the apo and calcium troponin-C regulatory domains: the muscle contraction… · the same entry in another collection · chain A against A, TM-score 1.00
- P02588 · AlphaFold monomer V2.0 prediction for troponin C, skeletal muscle (P02588) · a predicted model of the same protein · chain A against A, TM-score 0.61
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02588
- Elsewhere: RCSB PDB 1TNP · PDBe 1TNP · UniProt P02588
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.