MolNFT v1 · #22788 · protein
The structure of dengue virus E glycoprotein
1TG8 · Envelope glycoprotein: “The structure of dengue virus E glycoprotein”. X-ray diffraction, 1 ligand (NDG), 2 pockets (best druggability 0.50). MolNFT v1 #22788 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1TG8
- Type
- protein
- Length
- 390 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelope glycoprotein
- UniProt
- P27914
- Ligands
- NDG
- Pockets
- 2 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 6% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Envelope glycoprotein | protein | 390 | 6% helix, 46% strand | P27914 |
Ligands and binding sites
- NDG · 2-acetamido-2-deoxy-alpha-D-glucopyranose · sugar · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.50 | 0.79 | 32 | empty |
| 2 | 82 | 0.40 | 0.78 | 20 | empty |
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 1TG8 · The structure of Dengue virus E glycoprotein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27914
- Elsewhere: RCSB PDB 1TG8 · PDBe 1TG8 · UniProt P27914
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