MolNFT v1 · #22775 · protein
Crystal structure of a buffalo signaling glycoprotein (spb-40) secreted during involution
1TFV · Mammary gland protein 40: “Crystal structure of a buffalo signaling glycoprotein (spb-40) secreted during involution”. X-ray diffraction, 1 ligand (NAG), 3 pockets (best druggability 0.67). MolNFT v1 #22775 on GenesisL1: 3D…
- PDB
- 1TFV
- Type
- protein
- Length
- 361 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mammary gland protein 40
- Ligands
- NAG
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mammary gland protein 40 | protein | 361 | 35% helix, 22% strand | — |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 287 | 0.67 | 0.82 | 44 | empty |
| 2 | 167 | 0.49 | 0.77 | 21 | empty |
| 3 | 56 | 0.30 | 0.75 | 16 | empty |
Modifications
Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 1TFV · Crystal structure of a buffalo signaling glycoprotein (spb-40) secreted during involution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1TFV · PDBe 1TFV
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