MolNFT v1 · #22755 · protein

Ovotransferrin, N-terminal lobe, apo form

1TFA · Protein (ovotransferrin): “Ovotransferrin, N-terminal lobe, apo form”. X-ray diffraction, 1 ligand (SO4), 3 pockets (best druggability 0.46). MolNFT v1 #22755 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1TFA
Type: protein
Length: 329 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (ovotransferrin)
UniProt: P02789
Ligands: SO4
Pockets: 3 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (ovotransferrin)	protein	329	35% helix, 20% strand	P02789

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	135	0.46	0.77	23	empty
2	156	0.42	0.74	34	SO4
3	62	0.29	0.74	13	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

1TFA · Ovotransferrin, N-terminal lobe, apo form · the same entry in another collection · chain A against A, TM-score 1.00
P02789 · AlphaFold monomer V2.0 prediction for ovotransferrin (P02789) · a predicted model of the same protein · chain A against A, TM-score 0.69

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02789
Elsewhere: RCSB PDB 1TFA · PDBe 1TFA · UniProt P02789

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