MolNFT v1 · #22639 · protein
Structure of tetraubiquitin shows how multiubiquitin chains can be formed
1TBE: “Structure of tetraubiquitin shows how multiubiquitin chains can be formed”. X-ray diffraction, 1 pocket (best druggability 0.47). MolNFT v1 #22639 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1TBE
- Type
- protein
- Length
- 148 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tetraubiquitin
- UniProt
- P62988
- Pockets
- 1 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 25% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tetraubiquitin | protein | 76 | 24% helix, 33% strand | P62988 |
| B | Tetraubiquitin | protein | 72 | 26% helix, 36% strand | P62988 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 144 | 0.47 | 0.78 | 28 | empty |
Interfaces
1 interface between chains.
- A–B · 345 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 isopeptide (isopeptide).
Compared structures
- 1TBE · Structure of tetraubiquitin shows how multiubiquitin chains can be formed · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62988
- Elsewhere: RCSB PDB 1TBE · PDBe 1TBE · UniProt P62988
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