MolNFT v1 · #22575 · protein
Crystal structure of MUKF(1-287)
1T98 · Chromosome partition protein mukf: “Crystal structure of MUKF(1-287)”. X-ray diffraction, 6 pockets (best druggability 0.84). MolNFT v1 #22575 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1T98
- Type
- protein
- Length
- 526 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chromosome partition protein mukf
- UniProt
- P60293
- Pockets
- 6 · best druggability 0.84
Structure
x-ray diffraction · 2 distinct chains · 79% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chromosome partition protein mukf | protein | 266 | 80% helix, 4% strand | P60293 |
| B | Chromosome partition protein mukf | protein | 260 | 78% helix, 4% strand | P60293 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1144 | 0.84 | 0.85 | 86 | empty |
| 2 | 52 | 0.71 | 0.99 | 18 | empty |
| 3 | 174 | 0.48 | 0.76 | 19 | empty |
| 4 | 94 | 0.35 | 0.74 | 13 | empty |
| 5 | 50 | 0.33 | 0.78 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 3879 Ų buried · 31 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60293
- Elsewhere: RCSB PDB 1T98 · PDBe 1T98 · UniProt P60293
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