MolNFT v1 · #22543 · protein

Structure of the C-type lectin domain of CD23

1T8C · Low affinity immunoglobulin epsilon Fc receptor: “Structure of the C-type lectin domain of CD23”. Solution nmr, 1 pocket (best druggability 0.24). MolNFT v1 #22543 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1T8C
Type: protein
Length: 143 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Low affinity immunoglobulin epsilon Fc receptor
UniProt: P06734
Pockets: 1 · best druggability 0.24

Structure

solution nmr · 1 distinct chain · 15% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Low affinity immunoglobulin epsilon Fc receptor	protein	143	15% helix, 27% strand	P06734

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	51	0.24	0.72	16	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

1T8C · Structure of the C-type lectin domain of CD23 · the same entry in another collection · chain A against A, TM-score 1.00
P06734 · AlphaFold monomer V2.0 prediction for low affinity immunoglobulin epsilon Fc receptor… · a predicted model of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06734
Elsewhere: RCSB PDB 1T8C · PDBe 1T8C · UniProt P06734

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