MolNFT v1 · #22414 · DNA
Crystal structure of a DNA decamer containing a thymine- dimer
1T4I · 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3': “Crystal structure of a DNA decamer containing a thymine- dimer”. X-ray diffraction, 1 pocket (best druggability 0.59). MolNFT v1 #22414 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1T4I
- Type
- DNA
- Length
- 40 nucleotides
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3'; 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3'
- Pockets
- 1 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3' | dna | 10 | — | — |
| B, D | 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3' | dna | 10 | — | — |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 377 | 0.59 | 0.76 | 21 | empty |
Interfaces
6 interfaces between chains.
- A–B · 447 Ų buried · 60 hydrogen bonds · nucleic-nucleic
- C–D · 431 Ų buried · 58 hydrogen bonds · nucleic-nucleic
- B–D · 44 Ų buried · 1 hydrogen bond · nucleic-nucleic
- B–C · 35 Ų buried · 0 hydrogen bonds · nucleic-nucleic
- A–D · 21 Ų buried · 0 hydrogen bonds · nucleic-nucleic
Compared structures
- 1T4I · Crystal Structure of a DNA Decamer Containing a Thymine-dimer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1T4I · PDBe 1T4I
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.