MolNFT v1 · #22390 · protein
Structural analysis of the voltage-dependent calcium channel beta subunit functional core
1T3S · Dihydropyridine-sensitive L-type, calcium channel beta-2…: “Structural analysis of the voltage-dependent calcium channel beta subunit functional core”. X-ray diffraction, 1 ligand (HG), 3 pockets (best druggability 0.39). MolNFT v1…
- PDB
- 1T3S
- Type
- protein
- Length
- 294 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit
- UniProt
- P54288
- Ligands
- HG
- Pockets
- 3 · best druggability 0.39
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydropyridine-sensitive L-type, calcium channel beta-2 subunit | protein | 294 | 43% helix, 19% strand | P54288 |
Ligands and binding sites
- HG · Mercury (II) ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 60 | 0.39 | 0.80 | 17 | empty |
| 2 | 78 | 0.35 | 0.76 | 15 | empty |
| 3 | 54 | 0.35 | 0.78 | 12 | empty |
Compared structures
- 1T3S · Structural Analysis of the Voltage-Dependent Calcium Channel Beta Subunit Functional Core · the same entry in another collection · chain A against A, TM-score 1.00
- P54288 · AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54288
- Elsewhere: RCSB PDB 1T3S · PDBe 1T3S · UniProt P54288
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