MolNFT v1 · #22361 · protein
Glactose oxidase C383S mutant identified by directed evolution
1T2X · Galactose oxidase: “Glactose oxidase C383S mutant identified by directed evolution”. X-ray diffraction, 2 ligands (NA, CU), 3 pockets (best druggability 0.48). MolNFT v1 #22361 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 1T2X
- Type
- protein
- Length
- 639 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Galactose oxidase
- EC
- 1.1.3.9
- Ligands
- NA, CU
- Pockets
- 3 · best druggability 0.48
Structure
x-ray diffraction · 1 distinct chain · 3% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Galactose oxidase (EC 1.1.3.9) | protein | 639 | 3% helix, 42% strand | — |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
- CU · Copper (II) ion · metal · chains A
- ACT · Acetate ion · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 195 | 0.48 | 0.75 | 34 | empty |
| 2 | 145 | 0.44 | 0.76 | 27 | empty |
| 3 | 103 | 0.43 | 0.78 | 19 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1T2X · Glactose oxidase C383S mutant identified by directed evolution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1T2X · PDBe 1T2X
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