MolNFT v1 · #22240 · protein

Crystal structure of the C-terminus of TIP47

1SZI · Mannose-6-phosphate receptor binding protein 1: “Crystal structure of the C-terminus of TIP47”. X-ray diffraction, 2 pockets (best druggability 0.67). MolNFT v1 #22240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1SZI
Type: protein
Length: 194 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mannose-6-phosphate receptor binding protein 1
UniProt: Q9DBG5
Pockets: 2 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mannose-6-phosphate receptor binding protein 1	protein	194	70% helix, 7% strand	Q9DBG5

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.67	0.91	26	empty
2	64	0.38	0.79	17	empty

Compared structures

1SZI · Crystal Structure of the C-terminus of TIP47 · the same entry in another collection · chain A against A, TM-score 1.00
Q9DBG5 · AlphaFold monomer V2.0 prediction for perilipin-3 (Q9DBG5) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9DBG5
Elsewhere: RCSB PDB 1SZI · PDBe 1SZI · UniProt Q9DBG5

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