MolNFT v1 · #22219 · protein

Crystal structure of signalling protein from goat spg-40 in the presense of N,N',N''-triacetyl-chitotriose at 2.6A resolution

1SYT · BP40: “Crystal structure of signalling protein from goat spg-40 in the presense of N,N',N''-triacetyl-chitotriose at…”. X-ray diffraction, 2 ligands (NAG, MAN), 4 pockets (best druggability 0.58). MolNFT v1 #22219 on GenesisL1: 3D…

PDB: 1SYT
Type: protein
Length: 361 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: BP40
Ligands: NAG, MAN
Pockets: 4 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 35% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	BP40	protein	361	35% helix, 24% strand	—

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
MAN · alpha-D-mannopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	243	0.58	0.79	44	empty
2	244	0.53	0.77	25	empty
3	88	0.35	0.74	16	empty
4	59	0.32	0.76	16	empty

Modifications

Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

1SYT · Crystal structure of signalling protein from goat SPG-40 in the presense of… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1SYT · PDBe 1SYT

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.