MolNFT v1 · #22195 · protein
1.0 a crystal structure of T121V mutant of nitrophorin 4 complexed with nitric oxide
1SY1: “1.0 a crystal structure of T121V mutant of nitrophorin 4 complexed with nitric oxide”. X-ray diffraction, 3 ligands (HEM, PO4, NO), 1 pocket (best druggability 0.75). MolNFT v1 #22195 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1SY1
- Type
- protein
- Length
- 184 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nitrophorin 4
- UniProt
- Q94734
- Ligands
- HEM, PO4, NO
- Pockets
- 1 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 14% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nitrophorin 4 | protein | 184 | 14% helix, 47% strand | Q94734 |
Ligands and binding sites
- HEM · Protoporphyrin IX containing Fe · ligand · chains A
- PO4 · Phosphate ion · ion · chains A
- NO · Nitric oxide · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 293 | 0.75 | 0.87 | 36 | HEM, NO |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1SY1 · 1.0 A Crystal Structure of T121V Mutant of Nitrophorin 4 Complexed with Nitric Oxide · the same entry in another collection · chain A against A, TM-score 1.00
- Q94734 · AlphaFold monomer V2.0 prediction for nitrophorin-4 (Q94734) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q94734
- Elsewhere: RCSB PDB 1SY1 · PDBe 1SY1 · UniProt Q94734
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