MolNFT v1 · #22123 · protein

Crystal structure of a designed selected ankyrin repeat protein in complex with the maltose binding protein

1SVX · Ankyrin repeat protein OFF7: “Crystal structure of a designed selected ankyrin repeat protein in complex with the maltose binding protein”. X-ray diffraction, 4 pockets (best druggability 0.65). MolNFT v1 #22123 on GenesisL1: 3D…

PDB: 1SVX
Type: protein
Length: 526 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ankyrin repeat protein OFF7; Maltose-binding periplasmic protein
UniProt: P02928
Pockets: 4 · best druggability 0.65

Structure

x-ray diffraction · 2 distinct chains · 47% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ankyrin repeat protein OFF7	protein	157	53% helix, 0% strand	—
B	Maltose-binding periplasmic protein	protein	369	44% helix, 21% strand	P02928

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	415	0.65	0.78	38	empty
2	396	0.59	0.76	48	empty
3	291	0.59	0.78	41	empty
4	81	0.34	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 675 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

1SVX · Crystal structure of a designed selected Ankyrin Repeat protein in complex with the… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02928
Elsewhere: RCSB PDB 1SVX · PDBe 1SVX · UniProt P02928

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