MolNFT v1 · #2205 · protein

Glycosyltransferase

1BPL · Alpha-1,4-glucan-4-glucanohydrolase: “Glycosyltransferase”. X-ray diffraction, 1 pocket (best druggability 0.56). MolNFT v1 #2205 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1BPL
Type: protein
Length: 469 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-1,4-glucan-4-glucanohydrolase
EC: 3.2.1.1
UniProt: P06278
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 29% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alpha-1,4-glucan-4-glucanohydrolase (EC 3.2.1.1)	protein	179	16% helix, 27% strand	P06278
B	Alpha-1,4-glucan-4-glucanohydrolase (EC 3.2.1.1)	protein	290	36% helix, 22% strand	P06278

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	360	0.56	0.75	40	empty

Interfaces

1 interface between chains.

A–B · 3116 Å² buried · 56 hydrogen bonds · protein-protein

Compared structures

1BPL · Glycosyltransferase · the same entry in another collection · chain A against A, TM-score 1.00
P06278 · AlphaFold monomer V2.0 prediction for alpha-amylase (P06278) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06278
Elsewhere: RCSB PDB 1BPL · PDBe 1BPL · UniProt P06278

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