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MolNFT v1 · #21941 · protein

Structure of SKI8P, a wd repeat protein involved in mRNA degradation and meiotic recombination

1SQ9 · Antiviral protein SKI8: “Structure of SKI8P, a wd repeat protein involved in mRNA degradation and meiotic recombination”. X-ray diffraction, 1 ligand (SO4), 2 pockets (best druggability 0.79). MolNFT v1 #21941 on GenesisL1: 3D…

PDB
1SQ9
Type
protein
Length
378 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Antiviral protein SKI8
UniProt
Q02793
Ligands
SO4
Pockets
2 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 4% helix, 52% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAntiviral protein SKI8protein3784% helix, 52% strandQ02793

Ligands and binding sites

  • SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16150.790.8563SO4
2510.290.7617empty

Compared structures

  • 1SQ9 · Structure of Ski8p, a WD repeat protein involved in mRNA degradation and meiotic… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q02793 · AlphaFold monomer V2.0 prediction for antiviral protein SKI8 (Q02793) · a predicted model of the same protein · chain A against A, TM-score 0.97

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