MolNFT v1 · #21805 · protein

Complex of the 70-kda soluble lytic transglycosylase with bulgecin a

1SLY: “Complex of the 70-kda soluble lytic transglycosylase with bulgecin a”. X-ray diffraction, 1 ligand (BLG), 9 pockets (best druggability 0.45). MolNFT v1 #21805 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1SLY
Type: protein
Length: 618 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 70-kda soluble lytic transglycosylase
EC: 3.2.1.-
UniProt: P03810
Ligands: BLG
Pockets: 9 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 70% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	70-kda soluble lytic transglycosylase (EC 3.2.1.-)	protein	618	70% helix, 0% strand	P03810

Ligands and binding sites

BLG · 4-O-(4-O-sulfonyl-N-acetylglucosamininyl)-5-methylhydroxy-L-proline-taurine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	82	0.45	0.81	17	empty
2	63	0.36	0.78	17	empty
3	56	0.35	0.79	14	empty
4	56	0.35	0.78	15	empty
5	77	0.34	0.76	16	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1SLY · Complex of the 70-kda soluble lytic transglycosylase with bulgecin a · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03810
Elsewhere: RCSB PDB 1SLY · PDBe 1SLY · UniProt P03810

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