MolNFT v1 · #21651 · protein
Crystal structure of the phosphotyrosine recognition domain SH2 of V-src complexed with tyrosine-phosphorylated peptides
1SHA · V-src SH2 domain: “Crystal structure of the phosphotyrosine recognition domain SH2 of V-src complexed with…”. X-ray diffraction. MolNFT v1 #21651 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1SHA
- Type
- protein
- Length
- 108 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- V-src SH2 domain; Phosphopeptide a
- EC
- 2.7.1.112
- UniProt
- P00524
Structure
x-ray diffraction · 2 distinct chains · 15% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V-src SH2 domain (EC 2.7.1.112) | protein | 103 | 16% helix, 32% strand | P00524 |
| B | Phosphopeptide a | protein | 5 | 0% helix, 0% strand | — |
Interfaces
1 interface between chains.
- A–B · 438 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (phosphorylation).
Compared structures
- 1SHA · Crystal structure of the phosphotyrosine recognition domain SH2 of V-src complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00524
- Elsewhere: RCSB PDB 1SHA · PDBe 1SHA · UniProt P00524
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