MolNFT v1 · #21591 · protein

Reduced state of amicyanin mutant P94F

1SFH: “Reduced state of amicyanin mutant P94F”. X-ray diffraction, 2 ligands (CU1, NA), 1 pocket (best druggability 0.26). MolNFT v1 #21591 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1SFH
Type: protein
Length: 210 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Amicyanin
UniProt: P22364
Ligands: CU1, NA
Pockets: 1 · best druggability 0.26

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 45% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Amicyanin	protein	105	3% helix, 45% strand	P22364

Ligands and binding sites

CU1 · Copper (I) ion · metal · 2 copies · chains A, B
NA · Sodium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.26	0.73	11	empty

Interfaces

1 interface between chains.

A–B · 314 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

1SFH · Reduced state of amicyanin mutant P94F · the same entry in another collection · chain A against A, TM-score 1.00
P22364 · AlphaFold monomer V2.0 prediction for amicyanin (P22364) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22364
Elsewhere: RCSB PDB 1SFH · PDBe 1SFH · UniProt P22364

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