MolNFT v1 · #21453 · protein

L-alanine dehydrogenase complexed with pyruvate

1SAY: “L-alanine dehydrogenase complexed with pyruvate”. X-ray diffraction, 1 ligand (PYR), 1 pocket (best druggability 0.71). MolNFT v1 #21453 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1SAY
Type: protein
Length: 361 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: L-alanine dehydrogenase
EC: 1.4.1.1
UniProt: O52942
Ligands: PYR
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	L-alanine dehydrogenase (EC 1.4.1.1)	protein	361	40% helix, 18% strand	O52942

Ligands and binding sites

PYR · Pyruvic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	699	0.71	0.78	69	PYR

Compared structures

1SAY · L-alanine dehydrogenase complexed with pyruvate · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O52942
Elsewhere: RCSB PDB 1SAY · PDBe 1SAY · UniProt O52942

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.