MolNFT v1 · #21367 · protein
Crystal structure of putative DNA binding protein SP_1288 from streptococcus pygenes
1S7O · Hypothetical UPF0122 protein SPY1201/SPYM3_0842/SPS1042/SPYM…: “Crystal structure of putative DNA binding protein SP_1288 from streptococcus pygenes”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #21367 on…
- PDB
- 1S7O
- Type
- protein
- Length
- 319 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical UPF0122 protein SPY1201/SPYM3_0842/SPS1042/SPYM18_1152
- UniProt
- P67253
- Pockets
- 1 · best druggability 0.30
Structure
x-ray diffraction · 3 distinct chains · 82% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hypothetical UPF0122 protein SPY1201/SPYM3_0842/SPS1042/SPYM18_1152 | protein | 106 | 83% helix, 0% strand | P67253 |
| B | Hypothetical UPF0122 protein SPY1201/SPYM3_0842/SPS1042/SPYM18_1152 | protein | 105 | 81% helix, 0% strand | P67253 |
| C | Hypothetical UPF0122 protein SPY1201/SPYM3_0842/SPS1042/SPYM18_1152 | protein | 108 | 81% helix, 0% strand | P67253 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 81 | 0.30 | 0.73 | 18 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1223 Ų buried · 12 hydrogen bonds · protein-protein
- A–C · 306 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 185 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1S7O · Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes · the same entry in another collection · chain A against A, TM-score 1.00
- P67253 · AlphaFold monomer V2.0 prediction for UPF0122 protein SPY_1201/M5005_SPY0916 (P67253) · a predicted model of the same protein · chain C against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P67253
- Elsewhere: RCSB PDB 1S7O · PDBe 1S7O · UniProt P67253
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