MolNFT v1 · #21357 · protein

Solution structure of hnf-6

1S7E · Hepatocyte nuclear factor 6: “Solution structure of hnf-6”. Solution nmr, 1 pocket (best druggability 0.33). MolNFT v1 #21357 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1S7E
Type: protein
Length: 147 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hepatocyte nuclear factor 6
UniProt: O08755
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 42% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hepatocyte nuclear factor 6	protein	147	42% helix, 0% strand	O08755

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	89	0.33	0.74	22	empty

Compared structures

1S7E · Solution structure of HNF-6 · the same entry in another collection · chain A against A, TM-score 1.00
O08755 · AlphaFold monomer V2.0 prediction for hepatocyte nuclear factor 6 (O08755) · a predicted model of the same protein · chain A against A, TM-score 0.35

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O08755
Elsewhere: RCSB PDB 1S7E · PDBe 1S7E · UniProt O08755

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