MolNFT v1 · #21344 · protein
Enhanced green fluorescent protein containing the Y66L substitution
1S6Z: “Enhanced green fluorescent protein containing the Y66L substitution”. X-ray diffraction, 2 ligands (CR0, CL), 2 pockets (best druggability 0.74). MolNFT v1 #21344 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1S6Z
- Type
- protein
- Length
- 226 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Green fluorescent protein
- Ligands
- CR0, CL
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 12% helix, 52% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Green fluorescent protein | protein | 226 | 12% helix, 52% strand | — |
Ligands and binding sites
- CR0 · [2-(1-amino-2-hydroxypropyl)-2-hydroxy-4-isobutyl-5-oxo-2,5-dihydro-1H-imidazol-1-yl]acetaldehyde · ligand · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 74 | 0.74 | 0.98 | 24 | CR0 |
| 2 | 54 | 0.36 | 0.79 | 18 | empty |
Modifications
Observed in the structure: 2 covalent (covalent ligand).
Compared structures
- 1S6Z · Enhanced Green Fluorescent Protein Containing the Y66L Substitution · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1S6Z · PDBe 1S6Z
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