MolNFT v1 · #21332 · protein
Solution structure of merb, the organomercurial lyase involved in the bacterial mercury resistance system
1S6L · Alkylmercury lyase: “Solution structure of merb, the organomercurial lyase involved in the bacterial mercury resistance system”. Solution nmr, 3 pockets (best druggability 0.68). MolNFT v1 #21332 on GenesisL1: 3D structure, binding…
- PDB
- 1S6L
- Type
- protein
- Length
- 192 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alkylmercury lyase
- EC
- 4.99.1.2
- UniProt
- P77072
- Pockets
- 3 · best druggability 0.68
Structure
solution nmr · 1 distinct chain · 27% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alkylmercury lyase (EC 4.99.1.2) | protein | 192 | 27% helix, 22% strand | P77072 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 254 | 0.68 | 0.84 | 40 | empty |
| 2 | 229 | 0.68 | 0.84 | 33 | empty |
| 3 | 121 | 0.47 | 0.78 | 19 | empty |
Compared structures
- 1S6L · Solution structure of MerB, the Organomercurial Lyase involved in the bacterial mercury… · the same entry in another collection · chain A against A, TM-score 1.00
- P77072 · AlphaFold monomer V2.0 prediction for alkylmercury lyase (P77072) · a predicted model of the same protein · chain A against A, TM-score 0.69
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P77072
- Elsewhere: RCSB PDB 1S6L · PDBe 1S6L · UniProt P77072
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.