MolNFT v1 · #21213 · protein
Crystal structure analysis of the human tub protein (isoform a) spanning residues 289 through 561
1S31 · Tubby isoform a: “Crystal structure analysis of the human tub protein (isoform a) spanning residues 289 through 561”. X-ray diffraction, 4 pockets (best druggability 0.53). MolNFT v1 #21213 on GenesisL1: 3D structure, binding sites…
- PDB
- 1S31
- Type
- protein
- Length
- 273 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tubby isoform a
- UniProt
- P50607
- Pockets
- 4 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 13% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tubby isoform a | protein | 273 | 13% helix, 33% strand | P50607 |
Ligands and binding sites
- PGE · Triethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 198 | 0.53 | 0.78 | 34 | empty |
| 2 | 50 | 0.41 | 0.82 | 15 | empty |
| 3 | 67 | 0.31 | 0.75 | 19 | empty |
| 4 | 62 | 0.31 | 0.75 | 15 | empty |
Compared structures
- 1S31 · Crystal Structure Analysis of the human Tub protein (isoform a) spanning residues 289… · the same entry in another collection · chain A against A, TM-score 1.00
- P50607 · AlphaFold monomer V2.0 prediction for tubby protein homolog (P50607) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50607
- Elsewhere: RCSB PDB 1S31 · PDBe 1S31 · UniProt P50607
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