MolNFT v1 · #21109 · protein
Crystal structure of the glycogen synthase from agrobacterium tumefaciens (non-complexed form)
1RZV · Glycogen synthase 1: “Crystal structure of the glycogen synthase from agrobacterium tumefaciens (non-complexed form)”. X-ray diffraction, 9 pockets (best druggability 0.79). MolNFT v1 #21109 on GenesisL1: 3D structure, binding sites…
- PDB
- 1RZV
- Type
- protein
- Length
- 954 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycogen synthase 1
- EC
- 2.4.1.21
- UniProt
- P0A3F3
- Pockets
- 9 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Glycogen synthase 1 (EC 2.4.1.21) | protein | 477 | 42% helix, 20% strand | P0A3F3 |
Pockets
9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 811 | 0.79 | 0.82 | 83 | empty |
| 2 | 655 | 0.73 | 0.80 | 61 | empty |
| 3 | 714 | 0.69 | 0.76 | 64 | empty |
| 4 | 707 | 0.69 | 0.76 | 66 | empty |
| 5 | 105 | 0.61 | 0.87 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 900 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 20 modified (engineered).
Compared structures
- 1RZV · Crystal structure of the glycogen synthase from Agrobacterium tumefaciens (non-complexed… · the same entry in another collection · chain A against A, TM-score 1.00
- P0A3F3 · AlphaFold monomer V2.0 prediction for glycogen synthase 1 (P0A3F3) · a predicted model of the same protein · chain B against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A3F3
- Elsewhere: RCSB PDB 1RZV · PDBe 1RZV · UniProt P0A3F3
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