MolNFT v1 · #20829 · protein
The RAS-binding domain of RAF-1 from rat, NMR, 1 structure
1RRB · RAF proto-oncogene SERINE/THREONINE-protein kinase: “The RAS-binding domain of RAF-1 from rat, NMR, 1 structure”. Solution nmr, 1 pocket (best druggability 0.57). MolNFT v1 #20829 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1RRB
- Type
- protein
- Length
- 76 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RAF proto-oncogene SERINE/THREONINE-protein kinase
- EC
- 2.7.1.-
- UniProt
- P11345
- Pockets
- 1 · best druggability 0.57
Structure
solution nmr · 1 distinct chain · 21% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RAF proto-oncogene SERINE/THREONINE-protein kinase (EC 2.7.1.-) | protein | 76 | 21% helix, 32% strand | P11345 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.57 | 0.88 | 20 | empty |
Compared structures
- 1RRB · The RAS-binding domain of RAF-1 from rat, NMR, 1 structure · the same entry in another collection · chain A against A, TM-score 1.00
- P11345 · AlphaFold monomer V2.0 prediction for RAF proto-oncogene SERINE/THREONINE-protein kinase… · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11345
- Elsewhere: RCSB PDB 1RRB · PDBe 1RRB · UniProt P11345
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