MolNFT v1 · #20687 · protein

NMR study of acid fibroblast growth factor bound to 1,3,6-naphthalene trisulphonate, 26 structures

1RML · Acidic fibroblast growth factor: “NMR study of acid fibroblast growth factor bound to 1,3,6-naphthalene trisulphonate, 26 structures”. Solution nmr, 1 ligand (NTS), 1 pocket (best druggability 0.40). MolNFT v1 #20687 on GenesisL1…

PDB: 1RML
Type: protein
Length: 131 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acidic fibroblast growth factor
UniProt: P05230
Ligands: NTS
Pockets: 1 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 2% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Acidic fibroblast growth factor	protein	131	2% helix, 27% strand	P05230

Ligands and binding sites

NTS · Naphthalene trisulfonate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.40	0.78	18	NTS

Compared structures

1RML · NMR study of acid fibroblast growth factor bound to 1,3,6-naphthalene trisulphonate, 26… · the same entry in another collection · chain A against A, TM-score 1.00
P05230 · AlphaFold monomer V2.0 prediction for fibroblast growth factor 1 (P05230) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P05230
Elsewhere: RCSB PDB 1RML · PDBe 1RML · UniProt P05230

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