MolNFT v1 · #2054 · protein
NADPH:FMN oxidoreductase from vibrio harveyi
1BKJ · NADPH-flavin oxidoreductase: “NADPH:FMN oxidoreductase from vibrio harveyi”. X-ray diffraction, 2 ligands (FMN, PO4), 2 pockets (best druggability 0.64). MolNFT v1 #2054 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1BKJ
- Type
- protein
- Length
- 460 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- NADPH-flavin oxidoreductase
- EC
- 1.6.99.-
- UniProt
- Q56691
- Ligands
- FMN, PO4
- Pockets
- 2 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | NADPH-flavin oxidoreductase (EC 1.6.99.-) | protein | 230 | 49% helix, 14% strand | Q56691 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
- PO4 · Phosphate ion · ion · 2 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 287 | 0.64 | 0.80 | 40 | PO4, FMN |
| 2 | 296 | 0.62 | 0.80 | 43 | PO4, FMN |
Interfaces
1 interface between chains.
- A–B · 4613 Ų buried · 60 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q56691
- Elsewhere: RCSB PDB 1BKJ · PDBe 1BKJ · UniProt Q56691
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.