MolNFT v1 · #20418 · protein
Localisation of dynein light chains 1 and 2 and their pro-apoptotic ligands
1RE6 · Dynein light chain 2: “Localisation of dynein light chains 1 and 2 and their pro-apoptotic ligands”. Solution nmr, 2 pockets (best druggability 0.36). MolNFT v1 #20418 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1RE6
- Type
- protein
- Length
- 188 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dynein light chain 2
- Pockets
- 2 · best druggability 0.36
Structure
solution nmr · 1 distinct chain · 34% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Dynein light chain 2 | protein | 94 | 34% helix, 17% strand | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.36 | 0.75 | 20 | empty |
| 2 | 69 | 0.34 | 0.76 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 989 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 1RE6 · Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1RE6 · PDBe 1RE6
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