MolNFT v1 · #20382 · protein

Crystal structure of S. marcescens chitinase a mutant W167A

1RD6: “Crystal structure of S. marcescens chitinase a mutant W167A”. X-ray diffraction, 2 pockets (best druggability 0.72). MolNFT v1 #20382 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1RD6
Type: protein
Length: 540 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chitinase a
EC: 3.2.1.14
UniProt: P07254
Pockets: 2 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chitinase a (EC 3.2.1.14)	protein	540	27% helix, 27% strand	P07254

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	643	0.72	0.79	64	empty
2	111	0.43	0.78	30	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1RD6 · Crystal Structure of S. Marcescens Chitinase A Mutant W167A · the same entry in another collection · chain A against A, TM-score 1.00
P07254 · AlphaFold monomer V2.0 prediction for chitinase a (P07254) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07254
Elsewhere: RCSB PDB 1RD6 · PDBe 1RD6 · UniProt P07254

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